Tenofovir is a widely used antiviral medicine. Doctors prescribe it for HIV treatment, for HIV prevention (PrEP), and for chronic hepatitis B. You’ve probably seen two forms: tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF). They work the same way but behave differently in the body.
Both TDF and TAF block the virus from copying itself inside cells. TDF is older and is given at a higher dose. TAF is a newer form that delivers more drug inside target cells while keeping lower levels in the blood. That often means TAF has less impact on kidneys and bones for many people.
Common uses: - HIV treatment as part of combination therapy - PrEP to prevent HIV in people at risk (usually paired with emtricitabine) - Chronic hepatitis B to suppress the virus and protect the liver
Typical dosing varies: TDF is commonly 300 mg once daily, while TAF doses are lower (for example, 25 mg in some combinations). Don’t change or start doses on your own—your clinician will choose what fits your health and other meds.
Most people tolerate tenofovir well, but watch for a few known issues. TDF can affect kidney function and reduce bone mineral density in some patients. TAF usually has a lower risk of these problems, but it may raise blood lipids in some people. Other common effects include nausea, headache, and fatigue.
Your provider will usually check kidney function before you start and then regularly after that. Bone health checks may be advised if you have risk factors for osteoporosis. Tell your clinician about other medicines you take—some drugs can raise tenofovir levels or harm kidneys when combined.
If you notice new muscle pain, unexplained tiredness, dizziness, or changes in urination, contact your healthcare team. Those signs can point to kidney or other issues that need fast attention.
Want to buy tenofovir or PrEP online? Be careful. These medicines require a prescription in most places. Pick pharmacies that ask for a valid prescription, show a real business address, and have a licensed pharmacist you can contact. Avoid sites that sell at extremely low prices without requiring a prescription or offering any pharmacist support.
Check packaging for expiration dates and manufacturer details when your order arrives. If something looks off—wrong pills, missing leaflet, or damaged packaging—don’t take the medicine and report it to your pharmacy.
If you’re unsure whether tenofovir is right for you, ask a clinician. They’ll check your kidney tests, other meds, and infection risks to pick the safest option. A short conversation with a provider can prevent big problems down the road.
Tenofovir has become a mainstay in the fight against hepatitis B, thanks to its strong power to control the virus. This article covers how it works, what patients should expect, and tips for dealing with side effects. You'll also find the lowdown on why doctors pick tenofovir and stories about living well with hepatitis B. If you're looking for practical advice or real-life tips, this read will keep it simple and useful.
