Blood pressure medications: what to expect and how to use them safely
High blood pressure is common—about 1 in 3 adults in the US has it. That means many people will take one or more blood pressure medications. This page explains the main drug types, what side effects to watch for, and simple tips to get the best results from treatment.
Doctors pick medications based on your age, other health problems, and how high your numbers are. You might start with a single pill or a combination. The goal is lower readings and fewer risks for heart attack, stroke, and kidney damage.
Common types and what they do
Here are the main groups you’ll hear about:
Diuretics (water pills)—Help your body get rid of extra salt and water. They’re cheap and often the first choice. Watch for increased urination and low potassium.
ACE inhibitors—Relax blood vessels by blocking a hormone. They can cause a dry cough in some people and raise potassium levels.
ARBs (angiotensin II receptor blockers)—Work like ACE inhibitors but usually don’t cause the cough. Good option if you can’t tolerate an ACE inhibitor.
Beta-blockers—Slow the heart and lower pressure. They’re common after heart attacks and for certain arrhythmias. Examples include atenolol and propranolol. Some people notice tiredness, cold hands, or issues with exercise.
Calcium channel blockers—Keep blood vessels relaxed. They often help with chest pain and are useful for older adults. Side effects can include swelling in the ankles and headaches.
Side effects, interactions, and safety tips
All blood pressure drugs can cause side effects. The common ones are dizziness, tiredness, and changes in electrolytes (like potassium). Serious side effects are rarer but should be reported right away.
Watch out for drug interactions. For example, NSAIDs (ibuprofen) can blunt the effect of some blood pressure meds. Combining ACE inhibitors or ARBs with potassium supplements or potassium-sparing diuretics can raise potassium too high. Always tell your doctor about all prescriptions, supplements, and OTC meds you take.
If you’re worried about a specific drug—say atenolol and bone health or switching off Inderal—bring that up with your clinician. Recent articles note possible links between some beta-blockers and bone density, but the decision to change meds depends on your full health picture.
Practical tips: take pills at the same time each day, keep a log of home readings, and don’t stop drugs suddenly. If money or access is an issue, ask your pharmacist or doctor about lower-cost alternatives and safe online pharmacies that require a prescription.
Questions for your provider: What is my target blood pressure? Why this drug for me? What side effects should I expect? When will we check my labs? These short questions make visits more useful.
Good control of blood pressure saves lives. With the right drug, regular monitoring, and clear communication with your healthcare team, you can manage blood pressure effectively and stay active.