Benazepril Alternatives
Benazepril (Lotensin) is an ACE inhibitor many people use for high blood pressure. If it causes a dry cough, angioedema, or isn't a good fit because of pregnancy or kidney issues, there are clear alternatives. Below I list common options, why a doctor might pick them, and simple tips to switch safely.
Common drug alternatives
1) ARBs (angiotensin II receptor blockers). If you get a persistent cough on benazepril, an ARB like losartan or valsartan is the most common swap. ARBs work on the same blood-pressure pathway but cause far fewer coughs and less risk of angioedema.
2) Other ACE inhibitors. Sometimes the team will try a different ACE inhibitor such as lisinopril or enalapril. They act similarly, so this is less common if you had a bad side effect on benazepril.
3) Thiazide diuretics. Drugs like hydrochlorothiazide or chlorthalidone lower blood pressure by removing extra fluid and salt. They’re often used first-line or in combination with ACE inhibitors/ARBs.
4) Calcium channel blockers (CCBs). Amlodipine is a widely used CCB. These work well for older adults and people of African descent and can be combined with ACE inhibitors or ARBs.
5) Beta-blockers. Metoprolol and atenolol help with heart rate and blood pressure. They’re chosen when patients also have heart disease, arrhythmias, or certain forms of angina.
How to choose and switch safely
Which one is right depends on your health: pregnancy status, kidney function, potassium level, other meds, and side effects. Tell your doctor if you have a cough, swelling of the face or throat, or if you're planning a pregnancy—ACE inhibitors and ARBs are not safe in pregnancy.
When swapping meds your doctor will usually check blood pressure, kidney function (serum creatinine), and potassium within 1–2 weeks. Watch for lightheadedness when you start a new drug and avoid sudden heavy lifting or driving until you know how it affects you.
Tip: avoid potassium supplements or salt substitutes high in potassium unless your clinician approves—ACE inhibitors, ARBs, and some diuretics can raise potassium.
If you use over-the-counter NSAIDs regularly (ibuprofen, naproxen), mention that to your doctor. NSAIDs can blunt blood pressure meds and affect kidney function, especially when combined with ACE inhibitors or ARBs.
Finally, lifestyle matters. Reducing salt, losing a bit of weight, staying active, and cutting excessive alcohol often reduce how much medicine you need. But don’t stop or change prescription doses on your own—talk with your doctor or pharmacist about the safest plan for switching from benazepril to another option.
If you want, I can summarize alternatives based on a specific reason for switching (cough, pregnancy, kidney disease). Tell me why you need a change and I’ll tailor the list.
