Mark Cuban's Cost Plus Drug Company changed the game by showing clear math behind drug prices. Instead of mysterious markups, you see cost + a fixed 15% markup, a $3 pharmacy fee, and shipping. That model can make common generic medicines a lot cheaper than chains and middlemen.
Cost Plus lists the wholesale cost for each drug and then adds a flat 15% on top. You’ll also see a $3 dispensing fee and whatever shipping costs apply. Because the site shows the breakdown, you can compare the final number to your local pharmacy fast. No confusing rebates or hidden fees.
They focus mainly on generics and widely used chronic meds. For many daily pills—blood pressure drugs, statins, thyroid meds—the cost-plus model often beats the out-of-pocket price at big stores. Brands and specialty drugs may not be covered or may still be pricey.
Want to save money? start by checking the exact drug name and NDC (national drug code) to compare apples-to-apples with other sellers. Remember that Cost Plus usually requires a valid prescription. You’ll need to upload a script or have your prescriber send it.
Cost Plus generally doesn’t file claims with insurance, so this works best when you pay out of pocket. If you have high copays or a deductible, run the numbers: sometimes the site price beats your insurer’s cost, sometimes not. Also check shipping times—mail-order savings can be huge, but fast local pickup might still win in a pinch.
Watch for controlled substances and specialty meds. These often have extra rules, special handling, or limited availability. If your drug falls into those categories, contact the pharmacy first so you’re not surprised at checkout.
Want to compare options? our site covers similar services and alternatives. Read pieces like “How BlueSkyDrugs.com is Changing Online Pharmacies in 2025” or “Top Alternatives to rxconnected.com in 2025” to see other low-cost models and features. If you’re looking for a particular medication, try articles such as “How and Where to Buy Prozac Online Safely in 2025” for step-by-step checks and safety tips.
One good habit: save screenshots of price breakdowns and your prescription confirmations. That makes it easier to track orders or contest charges if something goes wrong. Also check the pharmacy license and shipping origin—these are simple checks that protect you from scams.
Bottom line: Cost Plus Drug Company makes prices more transparent and often lowers costs for common generics. It’s not a fit for every drug or every patient, but if you buy chronic generics out-of-pocket, it’s worth a quick price check. Use the price breakdown, confirm prescription rules, compare shipping, and you’ll know fast whether it’s the cheaper option for your meds.
In a move to make fertility treatments more accessible, Cosette Pharmaceuticals has teamed up with Mark Cuban Cost Plus Drug Company. Their alliance aims to offer Clomid® at a significantly reduced cost. This partnership marks a significant step toward improving fertility care affordability, benefiting countless couples.
